2-Bromo-1-[4-(trifluoromethoxy)phenyl]ethan-1-one → HCID 123188172, Verbindung
Reaktionsgleichung
[CH2:1]([O:8][C:9]([NH:11][C:12]1([CH2:18][C:19]([OH:21])=[O:20])[CH2:17][CH2:16][CH2:15][O:14][CH2:13]1)=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Br[CH2:23][C:24]([C:26]1[CH:31]=[CH:30][C:29]([O:32][C:33]([F:36])([F:35])[F:34])=[CH:28][CH:27]=1)=[O:25]>>[CH2:1]([O:8][C:9]([NH:11][C:12]1([CH2:18][C:19]([O:21][CH2:23][C:24](=[O:25])[C:26]2[CH:31]=[CH:30][C:29]([O:32][C:33]([F:34])([F:35])[F:36])=[CH:28][CH:27]=2)=[O:20])[CH2:17][CH2:16][CH2:15][O:14][CH2:13]1)=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1Komponenten
3
Reaktionsbedingungen
- Temperatur
- 50 °C
Versuchsvorschrift
Prepared by Method F using (3-{[(benzyloxy)carbonyl]amino}tetrahydro-2H-pyran-3-yl)-acetic acid (Preparation 23, 0.6 g, 2.05 mmol) and 2-bromo-1-[4-(trifluoromethoxy)-phenyl]ethanone (0.579 g, 0.205 mmol). The reaction was stirred at 50° C. for 1.5 hours.
Aufarbeitung
- customPrepared by Method F