Reaktionsgleichung
[CH3:1][NH2:2].[Br:3][C:4]1[CH:9]=[CH:8][C:7]([C:10]([F:13])([F:12])[F:11])=[CH:6][C:5]=1[S:14](Cl)(=[O:16])=[O:15]>>[Br:3][C:4]1[CH:9]=[CH:8][C:7]([C:10]([F:13])([F:12])[F:11])=[CH:6][C:5]=1[S:14]([NH:2][CH3:1])(=[O:16])=[O:15]Komponenten
3
Versuchsvorschrift
The title compound was prepared in a manner similar to that described for Intermediate EU using methylamine and 2-bromo-5-(trifluoromethyl)benzene-1-sulfonyl chloride. 1H NMR (500 MHz, CDCl3) δ 8.46-8.29 (d, J=2.4, 1H), 7.99-7.79 (d, J=8.3, 1H), 7.79-7.59 (dd, J=8.3, 2.3, 1H), 5.20-5.01 (d, J=6.4, 1H), 2.80-2.56 (d, J=5.3, 3H).
Quellen und Nachweise
- ORD-Eintrag
- ord-8c0ee77f57864c6f9944ffdae337dfac
- Quelldatensatz
- uspto-grants-2015_07
- Patentnummer
- US09079866B2
Verknüpfte Notizen
Wird geladen…