2-Chloro-4-methylquinoline → 2-{5-[(2,4-Dimethoxyphenyl)carbonyl]hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-4-methylquinoline

HRID 1525039

Reaktionsgleichung

Reaktionsgleichung von HRID 1525039
[CH3:1][O:2][C:3]1[CH:8]=[C:7]([O:9][CH3:10])[CH:6]=[CH:5][C:4]=1[C:11]([N:13]1[CH2:20][CH:19]2[CH:15]([CH2:16][NH:17][CH2:18]2)[CH2:14]1)=[O:12].Cl[C:22]1[CH:31]=[C:30]([CH3:32])[C:29]2[C:24](=[CH:25][CH:26]=[CH:27][CH:28]=2)[N:23]=1>>[CH3:1][O:2][C:3]1[CH:8]=[C:7]([O:9][CH3:10])[CH:6]=[CH:5][C:4]=1[C:11]([N:13]1[CH2:20][CH:19]2[CH2:18][N:17]([C:22]3[CH:31]=[C:30]([CH3:32])[C:29]4[C:24](=[CH:25][CH:26]=[CH:27][CH:28]=4)[N:23]=3)[CH2:16][CH:15]2[CH2:14]1)=[O:12]

Komponenten

3

Edukt 2

HCID 694492-Chloro-4-methylquinolineHCID 66211208(2,4-Dimethoxy-phenyl)-(hexahydro-pyrrolo[3,4-c]pyrrol-2-yl)-methanone

Produkt 1

HCID 671164562-{5-[(2,4-Dimethoxyphenyl)carbonyl]hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-4-methylquinoline

Versuchsvorschrift

The title compound was prepared in a manner analogous to Example 15 utilizing Intermediate 38 and 2-chloro-4-methyl-quinoline. MS (ESI) mass calcd. for C25H27N3O3, 417.51; m/z found, 418.3 [M+H]+.

Quellen und Nachweise

ORD-Eintrag
ord-1437846e847f49159768a5f7f0568c6e
Quelldatensatz
uspto-grants-2015_07
Patentnummer
US09079911B2

Verknüpfte Notizen

Wird geladen…