Ethanol → 4-Benzofuran-2-yl-2,8-dimethyl-1,2,3,4-tetrahydroisoquinoline, maleate salt

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Reaktionsschritte

4-benzofuran-2-yl-2,8-dimethyl-1,2,3,4-tetrahydroisoquinoline, maleate salt (99.0% AUC HPLC) was prepared as described in Example 26 from 2-acetylbenzofuran and 2-tolylmethylamine: 1H NMR (300 MHz, MeOD) δ□ 7.57 (d, J=6.9 Hz, 1H), □ 7.43 (d, J=8.1 Hz, 1H), 7.10-7.31 (m, 5H), 6.67 (s, 1H), 6.21 (s, 2H), 4.87-4.89 (m, 1H), 4.51 (s, 2H), 3.89-3.93 (m, 2H), 3.15 (s, 3H), 2.35 (s, 3H), EI MS m/z=278 [C19H19NO+H]+. Anal. Calcd. for C23H23NO5: C, 69.39; H, 6.00; N, 3.45 with 0.46% H2O and 2.5% EtOH. Found: C, 68.38; H, 6.30; N, 3.30.

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