Vinylcyclohexene → HCID 76514859, Verbindung

HRID 1527836Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1527836
[CH3:1][C:2]1([CH3:9])[CH2:7][CH2:6][C:5](=[O:8])[CH:4]=[CH:3]1.[CH:10]([C:12]1[CH2:17][CH2:16][CH2:15][CH2:14][CH:13]=1)=[CH2:11]>>[CH:12]1([CH2:10][CH2:11][CH:3]2[C:2]([CH3:9])([CH3:1])[CH2:7][CH2:6][C:5](=[O:8])[CH2:4]2)[CH2:17][CH2:16][CH2:15][CH2:14][CH2:13]1

Komponenten

3

Edukt 2

HCID 17497VinylcyclohexeneHCID 1368392-Cyclohexen-1-one, 4,4-dimethyl-

Produkt 1

HCID 76514859HCID 76514859, VerbindungAusbeute 75 %

Versuchsvorschrift

Using 4,4-dimethylcyclohex-2-enone (53 μL, 0.40 mmol) as substrate and vinylcyclohexene (0.14 mL, 1 mmol, 2.5 eq) as reagent and following General Procedure 3 overnight gave the above product (72 mg, 0.30 mmol, 75%) as a colourless oil after purification by column chromatography (1:49 EtOAc/petrol). The product compound was characterised using 1H NMR and 13C NMR, IR and MS. The presence of an enantioexcess was determined by derivatization using the procedure described in Example 1.

Aufarbeitung

  1. customGeneral Procedure 3 overnight

Quellen und Nachweise

ORD-Eintrag
ord-22c76dd00819494481b327f9bddc8675
Quelldatensatz
uspto-grants-2015_07
Patentnummer
US09090545B2

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