HCID 66687043, Verbindung → 4-(4-chlorophenyl)-5-(2,2,2-trifluoroethoxy)-N-((5-(trifluoromethyl)isoxazol-3-yl)methyl)picolinamide
Reaktionsgleichung
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[C:13]([O:14][CH2:15][C:16]([F:19])([F:18])[F:17])=[CH:12][N:11]=[C:10]([C:20]([OH:22])=O)[CH:9]=2)=[CH:4][CH:3]=1.Cl.[F:24][C:25]([F:34])([F:33])[C:26]1[O:30][N:29]=[C:28]([CH2:31][NH2:32])[CH:27]=1>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[C:13]([O:14][CH2:15][C:16]([F:18])([F:19])[F:17])=[CH:12][N:11]=[C:10]([C:20]([NH:32][CH2:31][C:28]3[CH:27]=[C:26]([C:25]([F:34])([F:33])[F:24])[O:30][N:29]=3)=[O:22])[CH:9]=2)=[CH:6][CH:7]=1Komponenten
3
Versuchsvorschrift
The title compound was synthesized in analogy to Example 1, using 4-(4-chloro-phenyl)-5-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboxylic acid (example D) and 5-trifluoromethyl-isoxazol-3-methanamine hydrochloride (example BG) as starting materials; LC-MS (UV peak area/ESI) 100%, 480.0532 (M+H)+.
Quellen und Nachweise
- ORD-Eintrag
- ord-bcbb50c79c7e445aa0f27bbecd006a0f