(3-Methyl-1,2,4-oxadiazol-5-yl)methanamine → 5-(4-chlorophenyl)-N-((3-methyl-1,2,4-oxadiazol-5-yl)methyl)-6-(2,2,2-trifluoroethoxy)nicotinamide

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	(3-Methyl-1,2,4-oxadiazol-5-yl)methanamine	HCID 10844548	—
Edukt	5-(4-Chloro-phenyl)-6-(2,2,2-trifluoro-ethoxy)-nicotinic acid	HCID 66686971	—
Produkt	5-(4-chlorophenyl)-N-((3-methyl-1,2,4-oxadiazol-5-yl)methyl)-6-(2,2,2-trifluoroethoxy)nicotinamide	HCID 56929463	—

Reaktionsschritte

The title compound was synthesized in analogy to Example 1 using 5-(4-chloro-phenyl)-6-(2,2,2-trifluoro-ethoxy)-nicotinic acid (CAN 1018782-82-5) and 3-methyl-1,2,4-oxadiazole-5-methanamine (CAN 90928-92-0) as starting materials; LC-MS (UV peak area/ESI) 100%, 425.0644 (M−H)−.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US09090599B2
Quelldatensatz	uspto-grants-2015_07
ORD ID	ord-65674885f5214259ad497e7692a2a497
Quellennotiz	uspto-grants-2015_07