Ethyl 4-methylidenecyclohexane-1-carboxylate → 4-Methylenecyclohexylmethanol
Reaktionsgleichung
C([O:3][C:4]([CH:6]1[CH2:11][CH2:10][C:9](=[CH2:12])[CH2:8][CH2:7]1)=O)C.[H-].[H-].[H-].[H-].[Li+].[Al+3]>>[CH2:12]=[C:9]1[CH2:10][CH2:11][CH:6]([CH2:4][OH:3])[CH2:7][CH2:8]1Komponenten
3
Versuchsvorschrift
The reduction reaction of 4-methylene-cyclohexanecarboxylic acid ethyl ester with LAH is as described in the above reference. The product was purified by distillation to provide (4-methylene-cyclohexyl)-methanol as clear oil (3.67 g, 29.09 mmol, 50% over Step A and B).
Aufarbeitung
- distillationThe product was purified by distillation
Quellen und Nachweise
- ORD-Eintrag
- ord-3c57686b1d0049178aa5b0b71d067ff8
- Quelldatensatz
- uspto-grants-2010_06
- Patentnummer
- US07732449B2
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