HCID 54173602, Verbindung → HCID 13885606, Verbindung

HRID 1530748Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1530748
[O:1]([C:8]1[CH:9]=[C:10]([CH2:14][CH2:15][CH:16]=[C:17]([C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)[C:18]([F:21])([F:20])[F:19])[CH:11]=[CH:12][CH:13]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[H][H]>C(O)C.[Ni]>[O:1]([C:8]1[CH:9]=[C:10]([CH2:14][CH2:15][CH2:16][CH:17]([C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)[C:18]([F:19])([F:20])[F:21])[CH:11]=[CH:12][CH:13]=1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Komponenten

5

Edukt 2

HCID 54173602HCID 54173602, VerbindungHCID 178418361HCID 178418361, Verbindung2×

Produkt 1

HCID 13885606HCID 13885606, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 935NickelKatalysatorHCID 702EthanolLösungsmittel

Versuchsvorschrift

4-(3-Phenoxyphenyl)-1-phenyl-1-trifluoromethyl-1-butene (3.18 g; 8.6 mmol) was hydrogenated in ethanol (40 ml) with hydrogen with the addition of Raney nickel (0.4 g) at room temperature and under atmospheric pressures. After the calculated amount of hydrogen had been taken up, the catalyst was filtered off and the solvent removed under reduced pressure. After chromatography on silica gel with hexane/toluene, there remained 2.49 g of product (=78% of theory).

Aufarbeitung

  1. filtrationthe catalyst was filtered off
  2. customthe solvent removed under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-30298c6f27244d23a3949a9eb7a69afe
Quelldatensatz
uspto-grants-2001_03
Patentnummer
USRE037087E1

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