HCID 15518370, Verbindung → HCID 22013785, Verbindung

HRID 1532646Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1532646
[ClH:1].C(OCC)(=O)C.[CH2:8]([C:29]1[N:33]([CH2:34][CH2:35][CH2:36][N:37]([CH3:39])[CH3:38])[C:32]2[CH:40]=[CH:41][CH:42]=[CH:43][C:31]=2[N:30]=1)[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH3:28]>C(OCC)(=O)C>[ClH:1].[CH2:8]([C:29]1[N:33]([CH2:34][CH2:35][CH2:36][N:37]([CH3:38])[CH3:39])[C:32]2[CH:40]=[CH:41][CH:42]=[CH:43][C:31]=2[N:30]=1)[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH3:28]

Komponenten

4

Edukt 2

HCID 15518370HCID 15518370, VerbindungHCID 21866389Hydrogen chloride-ethyl acetate

Produkt 1

HCID 22013785HCID 22013785, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 8857Ethyl AcetateLösungsmittel

Versuchsvorschrift

4N Hydrochloric acid/ethyl acetate solution (0.11 ml) was added to a solution containing 3-(2-henicosyl-1H-benzimidazol-1-yl)-N,N-dimethyl-1-propanamine (0.20 g) in ethyl acetate (2 ml). After being stirred for 20 minutes at room temperature, the reaction mixture was concentrated. The residue was recrystallized with the mixed solution of ethanol-ethyl acetate, thereby yielding the entitled compound (0.19 g) as white solid.

Aufarbeitung

  1. concentrationthe reaction mixture was concentrated
  2. customThe residue was recrystallized with the mixed solution of ethanol-ethyl acetate

Quellen und Nachweise

ORD-Eintrag
ord-91669861cc894b55a7fdec9684bdd122
Quelldatensatz
uspto-grants-2001_03
Patentnummer
US06204264B1

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