HCID 22013769, Verbindung → Ethyl 3-amino-4-[[3-(dimethylamino)propyl]amino]benzoate

HRID 1532658Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1532658
[CH3:1][N:2]([CH3:21])[CH2:3][CH2:4][CH2:5][NH:6][C:7]1[CH:17]=[CH:16][C:10]([C:11]([O:13][CH2:14][CH3:15])=[O:12])=[CH:9][C:8]=1[N+:18]([O-])=O>C(O)C.[C].[Pd]>[NH2:18][C:8]1[CH:9]=[C:10]([CH:16]=[CH:17][C:7]=1[NH:6][CH2:5][CH2:4][CH2:3][N:2]([CH3:21])[CH3:1])[C:11]([O:13][CH2:14][CH3:15])=[O:12]

Komponenten

4

Edukt 1

HCID 22013769HCID 22013769, Verbindung

Produkt 1

HCID 22013774Ethyl 3-amino-4-[[3-(dimethylamino)propyl]amino]benzoateAusbeute 101,9 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 178418390HCID 178418390, VerbindungKatalysatorHCID 702EthanolLösungsmittel

Versuchsvorschrift

10% of palladium-carbon (0.40 g) was added to a solution containing ethyl 4-{[3-(dimethylamino)propyl]amino}-3-nitrobenzoate (2.02 g) in ethanol (20 ml) and stirred for 5 hours under a hydrogen gas atmosphere at room temperature. After the catalyst was removed out by filtration, the filtrate was concentrated, thereby yielding the entitled compound (1.85 g) as dark red oil.

Aufarbeitung

  1. customAfter the catalyst was removed out by filtration
  2. concentrationthe filtrate was concentrated

Quellen und Nachweise

ORD-Eintrag
ord-cedc4bdd46bf4da08a0a95c3a88e3aad
Quelldatensatz
uspto-grants-2001_03
Patentnummer
US06204264B1

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