Ethanol → HCID 9828495, Verbindung

Reaktionsgleichung

[ClH:1].C(OCC)(=O)C.[CH3:8][N:9]1[CH2:14][CH2:13][N:12]([C:15]([C:17]2[N:21]([CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH3:39])[C:20]3[CH:40]=[CH:41][CH:42]=[CH:43][C:19]=3[N:18]=2)=[O:16])[CH2:11][CH2:10]1.C(O)C>C(OCC)(=O)C>[ClH:1].[CH3:8][N:9]1[CH2:10][CH2:11][N:12]([C:15]([C:17]2[N:21]([CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH3:39])[C:20]3[CH:40]=[CH:41][CH:42]=[CH:43][C:19]=3[N:18]=2)=[O:16])[CH2:13][CH2:14]1

Komponenten

Versuchsvorschrift

4N Hydrochloric acid/ethyl acetate solution (0.18 ml) was added to a solution containing 2-[(4-methylpiperazinyl)carbonyl]-1-octadecyl-1H-benzimidazole (0.348 g) in ethyl acetate (4 ml) and the mixture was stirred for 15 minutes at room temperature. The reaction mixture, with ethanol (1 ml) and ethyl acetate (4 ml) added thereto, was dissolved by heating, and then cooled with ice. The depositing crystals were collected by filtration, thereby yielding the entitled compound (0.318 g) as white solid.