HCID 22013773, Verbindung → HCID 22013746, Verbindung

HRID 1532695Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1532695
[CH3:1][N:2]([CH3:20])[CH2:3][CH2:4][NH:5][C:6]1[CH:16]=[CH:15][C:9]([C:10]([N:12]([CH3:14])[CH3:13])=[O:11])=[CH:8][C:7]=1[N+:17]([O-])=O>C(O)C.[C].[Pd]>[NH2:17][C:7]1[CH:8]=[C:9]([CH:15]=[CH:16][C:6]=1[NH:5][CH2:4][CH2:3][N:2]([CH3:20])[CH3:1])[C:10]([N:12]([CH3:14])[CH3:13])=[O:11]

Komponenten

4

Edukt 1

HCID 22013773HCID 22013773, Verbindung

Produkt 1

HCID 22013746HCID 22013746, VerbindungAusbeute 103,3 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 178418390HCID 178418390, VerbindungKatalysatorHCID 702EthanolLösungsmittel

Versuchsvorschrift

10% of palladium-carbon (0.535 g) was added to a solution containing 4-{[2-(dimethylamino)ethyl]amino}-N,N-dimethyl-3-nitrobenzamide (2.672 g) in ethanol (27 ml) and the mixture was stirred for 5.5 hours under a hydrogen gas atmosphere at room temperature. After the catalyst was removed out by filtration, the filtrate was concentrated, thereby yielding the entitled compound (2.464 g) as blackish brown oil.

Aufarbeitung

  1. customAfter the catalyst was removed out by filtration
  2. concentrationthe filtrate was concentrated

Quellen und Nachweise

ORD-Eintrag
ord-89184bdc515949dbb33433a613935788
Quelldatensatz
uspto-grants-2001_03
Patentnummer
US06204264B1

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