Benzenesulfonic Acid → Clopidogrel Besylate

Beteiligte Stoffe

Reaktionsschritte

Clopidogrel base was dissolved in acetone to obtain a clear solution. Then benzenesulfonic acid was added to the solution at 20° C. The reaction mixture was heated to reflux temperature for 2 to 10 hrs. The solvent was evaporated to dryness under reduced pressure to obtain the title salt as a powder.

Herkunft & Nachweise