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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 15385Erstellt: 24. Oktober 2026

Benzenesulfonic Acid → Clopidogrel Besylate

https://huagongshe.com/de/reaction/15385

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktBenzenesulfonic AcidHCID 7371—
EduktClopidogrelHCID 60606—
LösungsmittelMethanolHCID 887—
ProduktClopidogrel BesylateHCID 9847991—

Reaktionsschritte

Clopidogrel base was dissolved in methanol to obtain a clear solution. Benzenesulfonic acid was added to the solution at 20° C. The reaction mixture was heated to reflux temperature for 2 to 10 hrs. The solvent was evaporated to dryness under reduced pressure to obtain the title compound.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS07732608B2
Quelldatensatzuspto-grants-2010_06
ORD IDord-6048977fc62747ef9066cb73c267c532
Quellennotizuspto-grants-2010_06