HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Benzenesulfonic Acid → Clopidogrel Besylate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Benzenesulfonic Acid | HCID 7371 | — |
| Edukt | Clopidogrel | HCID 60606 | — |
| Lösungsmittel | Methanol | HCID 887 | — |
| Produkt | Clopidogrel Besylate | HCID 9847991 | — |
Reaktionsschritte
Clopidogrel base was dissolved in methanol to obtain a clear solution. Benzenesulfonic acid was added to the solution at 20° C. The reaction mixture was heated to reflux temperature for 2 to 10 hrs. The solvent was evaporated to dryness under reduced pressure to obtain the title compound.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07732608B2 |
| Quelldatensatz | uspto-grants-2010_06 |
| ORD ID | ord-6048977fc62747ef9066cb73c267c532 |
| Quellennotiz | uspto-grants-2010_06 |