HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Methyl Thioglycolate → Methyl 5-fluoro-1-benzothiophene-2-carboxylate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Methyl Thioglycolate | HCID 16907 | — |
| Edukt | Sodium hydride | HCID 24758 | — |
| Edukt | 2,5-Difluorobenzaldehyde | HCID 137663 | — |
| Produkt | Methyl 5-fluoro-1-benzothiophene-2-carboxylate | HCID 22473847 | — |
Reaktionsschritte
Using 5.0 g (35.2 mmol) of 2,5-difluorobenzaldehyde, 2.11 g (52.78 mmol) of sodium hydride (60% pure) and 4.11 g (38.7 mmol) of methyl mercaptoacetate, 1.1 g (14.3% of theory) of the title compound are obtained.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07732477B2 |
| Quelldatensatz | uspto-grants-2010_06 |
| ORD ID | ord-28aaadee87cc4a78bb55ccfaafe7e468 |
| Quellennotiz | uspto-grants-2010_06 |