HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Trifluoroacetic acid → {5-[Benzyl-(4-chloro-benzoyl)-amino]-2-propyl-benzoimidazol-1-yl}-acetic acid
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Trifluoroacetic acid | HCID 6422 | — |
| Edukt | {5-[Benzyl-(4-chloro-benzoyl)-amino]-2-propyl-benzoimidazol-1-yl}-acetic acid tert-butyl ester | HCID 67199607 | — |
| Produkt | {5-[Benzyl-(4-chloro-benzoyl)-amino]-2-propyl-benzoimidazol-1-yl}-acetic acid | HCID 59342502 | — |
Reaktionsschritte
{5-[Benzyl-(4-chloro-benzoyl)-amino]-2-propyl-benzoimidazol-1-yl}-acetic acid tert-butyl ester (0.12 mmol) was treated with TFA (2 mL) for 2 hours, concentrated, and purified by preparative LCMS to give the title compound. MS calculated for C26H24ClN3O3+H: 462, observed: 462.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07732618B2 |
| Quelldatensatz | uspto-grants-2010_06 |
| ORD ID | ord-db0f01f168c2425f892bce4e3e391d32 |
| Quellennotiz | uspto-grants-2010_06 |