Tetrahydrofuran → 3-(1-cyano-1-methylethyl)-N-{4-cyano-3-[(2-{[(4-methylpiperazin-1-yl)acetyl]amino}[1,3]thiazolo[5,4-b]pyridin-5-yl)oxy]phenyl}benzamide
Reaktionsgleichung
[CH3:38][CH2:39][N:40]([CH2:41][CH3:42])[CH2:43][CH3:44].[CH3:45][N:46]1[CH2:47][CH2:48][NH:49][CH2:50][CH2:51]1.[CH3:57][CH2:58][O:59][C:60](=[O:61])[CH3:62].[Cl:1][CH2:2][C:3](=[O:4])[NH:5][c:6]1[s:7][c:8]2[n:9][c:10]([O:15][c:16]3[cH:17][c:18]([NH:24][C:25]([c:26]4[cH:27][c:28]([C:32]([CH3:33])([CH3:34])[C:35]#[N:36])[cH:29][cH:30][cH:31]4)=[O:37])[cH:19][cH:20][c:21]3[C:22]#[N:23])[cH:11][cH:12][c:13]2[n:14]1.[O:52]1[CH2:53][CH2:54][CH2:55][CH2:56]1>>[CH2:2]([C:3](=[O:4])[NH:5][c:6]1[s:7][c:8]2[n:9][c:10]([O:15][c:16]3[cH:17][c:18]([NH:24][C:25]([c:26]4[cH:27][c:28]([C:32]([CH3:33])([CH3:34])[C:35]#[N:36])[cH:29][cH:30][cH:31]4)=[O:37])[cH:19][cH:20][c:21]3[C:22]#[N:23])[cH:11][cH:12][c:13]2[n:14]1)[N:49]1[CH2:48][CH2:47][N:46]([CH3:45])[CH2:51][CH2:50]1
