Ethyl Acetate → 3'-(Octadecylcarbamoyloxy)acrylanilide

HRID 1575999Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1575999
C(OCC)(=O)C.[OH:7][C:8]1[CH:9]=[C:10]([CH:16]=[CH:17][CH:18]=1)[NH:11][C:12](=[O:15])[CH:13]=[CH2:14].[CH2:19]([N:37]=[C:38]=[O:39])[CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH3:36]>C(N(CC)CC)C>[CH2:19]([NH:37][C:38]([O:7][C:8]1[CH:9]=[C:10]([CH:16]=[CH:17][CH:18]=1)[NH:11][C:12](=[O:15])[CH:13]=[CH2:14])=[O:39])[CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH3:36]

Komponenten

5

Edukt 3

HCID 8857Ethyl AcetateHCID 66988Octadecyl isocyanateHCID 275403n-(3-Hydroxyphenyl)acrylamide

Produkt 1

HCID 215129753'-(Octadecylcarbamoyloxy)acrylanilide

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 8471TriethylamineLösungsmittel

Reaktionsbedingungen

Temperatur
20 °C

Versuchsvorschrift

A reaction vessel is charged with 100 parts of ethyl acetate, 16.3 parts of 3'-hydroxyacrylanilide, 29.5 parts of octadecyl isocyanate and one part of triethylamine. The reaction mixture is heated at reflux for about 1 hour, cooled to 20°C and filtered. The solids are washed with ethyl acetate and air dried to give 40.5 parts of 3'-(octadecylcarbamoyloxy)acrylanilide, m.p. 124°-126°C.

Aufarbeitung

  1. temperatureThe reaction mixture is heated
  2. temperatureat reflux for about 1 hour
  3. filtrationfiltered
  4. washThe solids are washed with ethyl acetate and air
  5. customdried

Quellen und Nachweise

ORD-Eintrag
ord-9baf46efd9c34029b085dac9484bcec8
Quelldatensatz
uspto-grants-1976_09
Patentnummer
US03979202

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