Sodium Azide → 9-Methyltetrazolo[1,5-a]quinoxaline

HRID 1576011Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1576011
Cl[C:2]1[CH:3]=[N:4][C:5]2[C:10]([N:11]=1)=[C:9]([CH3:12])[CH:8]=[CH:7][CH:6]=2.[N-:13]=[N+:14]=[N-:15].[Na+]>C(O)C>[CH3:12][C:9]1[CH:8]=[CH:7][CH:6]=[C:5]2[C:10]=1[N:11]1[N:13]=[N:14][N:15]=[C:2]1[CH:3]=[N:4]2

Komponenten

4

Edukt 2

HCID 33557Sodium AzideHCID 215049212-Chloro-8-methylquinoxaline

Produkt 1

HCID 215048979-Methyltetrazolo[1,5-a]quinoxaline

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Versuchsvorschrift

The crude 3-chloro-5-methylquinoxaline obtained in the step above was stirred for 3 hours at reflux temperature in 75 ml. of ethanol containing 1.8 g. of sodium azide and 20 ml. of 1N HCL. When the reaction mixture was cooled, the product precipitated as needles. Recrystallization of the product from ethanol produced highly purified 9-methyltetrazolo[1,5-a]quinoxaline, m.p. 166°-68°C. The product was identified by NMR analysis and elemental microanalysis.

Aufarbeitung

  1. temperatureat reflux temperature in 75 ml
  2. temperatureWhen the reaction mixture was cooled
  3. customthe product precipitated as needles
  4. customRecrystallization of the product from ethanol

Quellen und Nachweise

ORD-Eintrag
ord-5c83a31fcb3f432dab99a957639fcced
Quelldatensatz
uspto-grants-1976_09
Patentnummer
US03979387

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