Methyl chloroformate → N-methoxycarbonylphthalimide

HRID 1576735Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1576735
[C:1]1(=[O:11])[NH:5][C:4](=[O:6])[C:3]2=[CH:7][CH:8]=[CH:9][CH:10]=[C:2]12.[K].[CH3:13][O:14][C:15](Cl)=[O:16]>>[CH3:13][O:14][C:15]([N:5]1[C:1](=[O:11])[C:2]2=[CH:10][CH:9]=[CH:8][CH:7]=[C:3]2[C:4]1=[O:6])=[O:16]

Komponenten

3

Edukt 2

HCID 6586Methyl chloroformateHCID 24194345Phthalimide potassium salt

Produkt 1

HCID 5043525N-methoxycarbonylphthalimide

Versuchsvorschrift

A suspension comprising 25 millimoles of potassium phthalimide and 20 ml of methylchloroformate is refluxed for a period of approximately 31/2 hours. Upon completion of refluxing, the reaction mediuim is cooled, filtered, with insolubles being removed continuously by treatment with hot acteone until only potassium chloride remains. The desired product m.p. 184° - 184.5°C., is obtained from the acetone.

Aufarbeitung

  1. temperatureis refluxed for a period of approximately 31/2 hours
  2. temperatureUpon completion of refluxing
  3. temperaturethe reaction mediuim is cooled
  4. filtrationfiltered, with insolubles
  5. custombeing removed continuously by treatment with hot acteone until only potassium chloride

Quellen und Nachweise

ORD-Eintrag
ord-3cb2362fdde641d6b9ac79938eaaa5ef
Quelldatensatz
uspto-grants-1976_09
Patentnummer
US03982891

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