Benzylamine → 75484-74-1

HRID 1577801Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1577801
[Cl:1][C:2]1[CH:7]=[C:6]([CH3:8])[N:5]=[C:4]([CH3:9])[C:3]=1[N+:10]([O-:12])=[O:11].[CH2:13]([NH2:20])[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1>C(O)(C)C>[ClH:1].[CH2:13]([NH:20][C:2]1[CH:7]=[C:6]([CH3:8])[N:5]=[C:4]([CH3:9])[C:3]=1[N+:10]([O-:12])=[O:11])[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1

Komponenten

4

Edukt 2

HCID 7504BenzylamineHCID 107027254-Chloro-2,6-dimethyl-3-nitropyridine

Produkt 1

HCID 2056958975484-74-1

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 3776IsopropanolLösungsmittel

Versuchsvorschrift

9.3 Grams (0.05 mol) of 4-chloro-2,6-dimethyl-3-nitropyridine and 10.7 g (0.1 mol) of benzylamine are heated for 5 hours at boiling point in 20 ml of isopropanol. After cooling, the mixture is concentrated, dissolved in water and extracted with chloroform. The chloroform phase is dried with sodium sulfate and concentrated. The residue is converted with ethanolic hydrochloric acid into the hydrochloride and recrystallized from isopropanol.

Aufarbeitung

  1. temperatureAfter cooling
  2. concentrationthe mixture is concentrated
  3. dissolutiondissolved in water
  4. extractionextracted with chloroform
  5. dry with materialThe chloroform phase is dried with sodium sulfate
  6. concentrationconcentrated
  7. customrecrystallized from isopropanol

Quellen und Nachweise

ORD-Eintrag
ord-29a122e524ff4855ad8c54d9ee8de13d
Quelldatensatz
uspto-grants-1981_09
Patentnummer
US04289765

Notizen zur Reaktion

Wird geladen…