Dimethyl-1,3-thiazole-5-carboxylic acid → 2,4-Dimethyl-N-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)-1,3-thiazole-5-carboxamide

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	Dimethyl-1,3-thiazole-5-carboxylic acid	HCID 736488	—
Edukt	3-(2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}aniline	HCID 49852105	—
Produkt	2,4-Dimethyl-N-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)-1,3-thiazole-5-carboxamide	HCID 11306286	68%

Reaktionsschritte

The title compound was prepared in 68% yield according to the general procedure for the preparation of the amides (Method C) starting from 3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}aniline (D6) and 2,4-dimethyl-1,3-thiazole-5-carboxylic acid.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US07732600B2
Quelldatensatz	uspto-grants-2010_06
ORD ID	ord-79badf2057394d658daaaa00bfa681cc
Quellennotiz	uspto-grants-2010_06