Chloroacetyl chloride → 4-chloro-N'-(2-chloroacetyl)benzohydrazide

HRID 1581

Reaktionsgleichung

Reaktionsgleichung von HRID 1581
[Cl:1][C:2]1[CH:11]=[CH:10][C:5]([C:6]([NH:8][NH2:9])=[O:7])=[CH:4][CH:3]=1.[Cl:12][CH2:13][C:14](Cl)=[O:15]>O1CCOCC1>[Cl:12][CH2:13][C:14]([NH:9][NH:8][C:6](=[O:7])[C:5]1[CH:10]=[CH:11][C:2]([Cl:1])=[CH:3][CH:4]=1)=[O:15]

Komponenten

4

Edukt 2

HCID 6577Chloroacetyl chlorideHCID 108164-Chlorobenzohydrazide

Produkt 1

HCID 5212924-chloro-N'-(2-chloroacetyl)benzohydrazide

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 312751,4-DioxaneLösungsmittel

Versuchsvorschrift

To a solution of p-chlorobenzoic hydrazide (11.2 g) in dioxane (100 ml) was added chloroacetyl chloride (6 ml). The resulting mixture was refluxed for three hours, cooled to room temperature and filtered. The resulting solid was washed with ethyl ether and dried to yield N'-chloroacetyl-4-chlorobenzoic hydrazide as white solid.

Aufarbeitung

  1. temperatureThe resulting mixture was refluxed for three hours
  2. filtrationfiltered
  3. washThe resulting solid was washed with ethyl ether
  4. customdried

Quellen und Nachweise

ORD-Eintrag
ord-7d8de4f9f5ac412ebeca703ef49f3390
Quelldatensatz
uspto-grants-1998_03
Patentnummer
US05726176

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