HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1,4-Dioxane hydrochloride → 2-Aminoindan-5-carboxylic acid morpholinamide hydrochloride
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1,4-Dioxane hydrochloride | HCID 20443148 | — |
| Edukt | 2-(Tert-butoxycarbonylamino)indan-5-carboxylic acid morpholinamide | HCID 131724366 | — |
| Lösungsmittel | Acetic Acid | HCID 176 | — |
| Produkt | 2-Aminoindan-5-carboxylic acid morpholinamide hydrochloride | HCID 69849846 | — |
Reaktionsschritte
Using 2-(tert-butoxycarbonylamino)indan-5-carboxylic acid morpholinamide (1.0 g, 2.7 mmol), 4N hydrochloric acid-dioxane (12 ml) and acetic acid (36 ml), a similar procedure to Example 24 was carried out to obtain 2-aminoindan-5-carboxylic acid morpholinamide hydrochloride (750 mg, 2.7 mmol) having the following physical properties:
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06734180B1 |
| Quelldatensatz | uspto-grants-2004_05 |
| ORD ID | ord-d2bbbb28ee2842fabf798561437395ef |
| Quellennotiz | uspto-grants-2004_05 |