Methyl morpholine oxide → 1-(1-Ethyl-6-isopropyl-4,4-dimethyl-1,2,3,4-tetrahydro-quinolin-8-yl)-propan-1-one
Reaktionsgleichung
[CH2:1]([N:3]1[C:12]2[C:7](=[CH:8][C:9]([CH:17]([CH3:19])[CH3:18])=[CH:10][C:11]=2[CH:13]([OH:16])[CH2:14][CH3:15])[C:6]([CH3:21])([CH3:20])[CH2:5][CH2:4]1)[CH3:2].C[N+]1([O-])CCOCC1>>[CH2:1]([N:3]1[C:12]2[C:7](=[CH:8][C:9]([CH:17]([CH3:19])[CH3:18])=[CH:10][C:11]=2[C:13](=[O:16])[CH2:14][CH3:15])[C:6]([CH3:21])([CH3:20])[CH2:5][CH2:4]1)[CH3:2]Komponenten
3
Versuchsvorschrift
Following General Procedure D, 1-(1-ethyl-6-isopropyl-4,4-dimethyl-1,2,3,4-tetrahydro-quinolin-8-yl)-propan-1-ol (Intermediate 10, 5.37 g, 21.3 mmol) and 4-methylmorpholine N-oxide (5.00 g, 42.6 mmol) were reacted to give the title compound as a yellow oil.
Aufarbeitung
- customwere reacted