Methyl iodide → Methyl 2-[4-(3-chlorophenyl)-1-ethyl-7-methyl-2-oxo-1,2-dihydro-1,8-naphthyridin-3-yl]benzoate

Beteiligte Stoffe

Reaktionsschritte

After the reaction of 3-(3-chlorobenzoyl)-2-ethylamino-6-methylpyridine with isochroman-1,3-dione (75%) under heating, the compound obtained by usual work-up was reacted with methyl iodide in 2-butanone in the presence of potassium carbonate. Thereafter, the reaction mixture was worked up and purified in a usual manner to obtain methyl 2-[4-(3-chlorophenyl)-1-ethyl-7-methyl-2-oxo-1,2-dihydro-1,8-naphthyridin-3-yl]benzoate as a yellow solid. MS: 433.

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