Hydrochloric Acid → 2-Amino-5-tert-butyl-4-(hexadecyloxy)phenol--hydrogen chloride (1/1)

HRID 1583920Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1583920
[C:1]([C:5]1[C:14]([O:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH3:31])=[CH:13][C:8]2[N:9]=C(C)[O:11][C:7]=2[CH:6]=1)([CH3:4])([CH3:3])[CH3:2].[ClH:32]>C(O)C>[ClH:32].[NH2:9][C:8]1[CH:13]=[C:14]([O:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH3:31])[C:5]([C:1]([CH3:4])([CH3:3])[CH3:2])=[CH:6][C:7]=1[OH:11]

Komponenten

4

Edukt 2

HCID 313Hydrochloric AcidHCID 13076757HCID 13076757, Verbindung

Produkt 1

HCID 130767632-Amino-5-tert-butyl-4-(hexadecyloxy)phenol--hydrogen chloride (1/1)Ausbeute 92 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Versuchsvorschrift

7.3 g of the benzoxazole compound obtained in Step (d) above was refluxed for 3 hours together with 30 ml of ethanol and 20 ml of concentrated hydrochloric acid. After the completion of the reaction, the reaction mixture was allowed to stand and cool. The crystals thus precipitated were collected by filtration, washed with water and then washed with acetone. Thus, 6.9 g (92% yield) of 2-amino-5-tert-butyl-4-hexadecyloxyphenol hydrochloride was obtained.

Aufarbeitung

  1. customAfter the completion of the reaction
  2. temperaturecool
  3. customThe crystals thus precipitated
  4. filtrationwere collected by filtration
  5. washwashed with water
  6. washwashed with acetone

Quellen und Nachweise

ORD-Eintrag
ord-9ae93751bd5944c3a27a1a3af9a0712a
Quelldatensatz
uspto-grants-1985_11
Patentnummer
US04555470

Notizen zur Reaktion

Wird geladen…