6-Chloronicotinic acid → 6-Chloro-N-[3-(1H-imidazol-1-yl)-2-methylpropyl]-3-pyridinecarboxamide
Reaktionsgleichung
[Cl:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([OH:8])=O)=[CH:4][N:3]=1.[N:11]1([CH2:16][CH:17]([CH3:20])[CH2:18][NH2:19])[CH:15]=[CH:14][N:13]=[CH:12]1>>[Cl:1][C:2]1[N:3]=[CH:4][C:5]([C:6]([NH:19][CH2:18][CH:17]([CH3:20])[CH2:16][N:11]2[CH:15]=[CH:14][N:13]=[CH:12]2)=[O:8])=[CH:9][CH:10]=1Komponenten
3
Versuchsvorschrift
When 6-chloronicotinic acid was reacted with 3-(1H-imidazol-1-yl)-2-methylpropanamine by the procedure of Example 20, the compound of the Example was obtained, mp 102°-104° C.
Quellen und Nachweise
- ORD-Eintrag
- ord-2f00c09a639d4026926c57303137cb5e
- Quelldatensatz
- uspto-grants-1985_11
- Patentnummer
- US04555519
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