2-Bromo-1-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethan-1-one → 5-[3-[3-Methoxy-4-[2-(5-methyl-2-phenyl-4-oxazolyl)-2-oxoethoxy]phenyl]propyl]-2,4-oxazolidinedione

HRID 1584314

Reaktionsgleichung

Reaktionsgleichung von HRID 1584314
[OH:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH2:9][CH2:10][CH:11]2[O:15][C:14](=[O:16])[NH:13][C:12]2=[O:17])=[CH:4][C:3]=1[O:18][CH3:19].Br[CH2:21][C:22]([C:24]1[N:25]=[C:26]([C:30]2[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=2)[O:27][C:28]=1[CH3:29])=[O:23]>>[CH3:19][O:18][C:3]1[CH:4]=[C:5]([CH2:8][CH2:9][CH2:10][CH:11]2[O:15][C:14](=[O:16])[NH:13][C:12]2=[O:17])[CH:6]=[CH:7][C:2]=1[O:1][CH2:21][C:22]([C:24]1[N:25]=[C:26]([C:30]2[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=2)[O:27][C:28]=1[CH3:29])=[O:23]

Komponenten

3

Edukt 2

HCID 149136502-Bromo-1-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethan-1-oneHCID 698304715-[3-(4-Hydroxy-3-methoxyphenyl)propyl]-2,4-oxazolidinedione

Produkt 1

HCID 212244175-[3-[3-Methoxy-4-[2-(5-methyl-2-phenyl-4-oxazolyl)-2-oxoethoxy]phenyl]propyl]-2,4-oxazolidinedione

Versuchsvorschrift

In substantially the same manner as in Working Example 9, 5-[3-(4-hydroxy-3-methoxyphenyl)propyl]-2,4-oxazolidinedione was reacted with 4-bromoacetyl-5-methyl-2-phenyloxazole to obtain 5-[3-[3-methoxy-4-[2-(5-methyl-2-phenyl-4-oxazolyl)-2-oxoethoxy]phenyl]propyl]-2,4-oxazolidinedione as an oily product.

Quellen und Nachweise

ORD-Eintrag
ord-5bfc4f91aeeb4e9d8ce0e82d0692e12c
Quelldatensatz
uspto-grants-1999_08
Patentnummer
US05932601

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