Tributylstannane → (E)-3-(tributylstannyl)prop-2-en-1-ol

HRID 1587015Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1587015
[CH2:1]([OH:4])[C:2]#[CH:3].[CH2:5]([SnH:9]([CH2:14][CH2:15][CH2:16][CH3:17])[CH2:10][CH2:11][CH2:12][CH3:13])[CH2:6][CH2:7][CH3:8]>C1(C)C=CC=CC=1>[CH2:14]([Sn:9]([CH2:5][CH2:6][CH2:7][CH3:8])([CH2:10][CH2:11][CH2:12][CH3:13])/[CH:3]=[CH:2]/[CH2:1][OH:4])[CH2:15][CH2:16][CH3:17]

Komponenten

4

Edukt 2

HCID 5948TributylstannaneHCID 7859Propargyl alcohol

Produkt 1

HCID 10043273(E)-3-(tributylstannyl)prop-2-en-1-ol

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 1140TolueneLösungsmittel

Versuchsvorschrift

To a mixture of propargyl alcohol (2.24 g) and α,α'-azoisobutyronitrile (0.10 g) in anhydrous toluene (150 ml) is added tributyltin hydride (12.9 ml) and the mixture heated at reflux for about 2.5 hours, cooled and concentrated in vacuo. The crude product is purified by flash chromatography in 15% ether in hexane to give the desired product.

Aufarbeitung

  1. temperaturethe mixture heated
  2. temperatureat reflux for about 2.5 hours
  3. temperaturecooled
  4. concentrationconcentrated in vacuo
  5. customThe crude product is purified by flash chromatography in 15% ether in hexane

Quellen und Nachweise

ORD-Eintrag
ord-96f7297063ff4536a13820f86abb994a
Quelldatensatz
uspto-grants-1993_06
Patentnummer
US05216015

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