Methanol → 3-Methyl-1-(2-piperidinophenyl)-1-butylamine, (S)-
Reaktionsgleichung
[CH3:1][CH:2]([CH3:18])[CH2:3][CH:4]([NH2:17])[C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=1[N:11]1[CH2:16][CH2:15][CH2:14][CH2:13][CH2:12]1.C(N[C@H](C(O)=O)CCC(O)=O)(=O)C.CO>CC(C)=O>[CH3:1][CH:2]([CH3:18])[CH2:3][C@H:4]([NH2:17])[C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=1[N:11]1[CH2:16][CH2:15][CH2:14][CH2:13][CH2:12]1Komponenten
5
Edukt 3
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
Equimolar quantities of racemic 3-methyl-1-(2-piperidino-phenyl)-1-butylamine and of N-acetyl-L-glutamic acid were refluxed in aceton, whereby methanol was added in such an amount to yield a clear solution.
Aufarbeitung
- customto yield a clear solution
Quellen und Nachweise
- ORD-Eintrag
- ord-87c5e5558fd54e07848bb08cd8904b15
- Quelldatensatz
- uspto-grants-1993_06
- Patentnummer
- US05216167
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