Sodium Hydroxide → HCID 14076219, Verbindung

HRID 1587903Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1587903
[C:1]([C:6]1[CH:11]=[CH:10][C:9]([CH2:12][CH2:13][NH:14][CH2:15][CH:16]([OH:27])[C:17]2[S:21][C:20]([NH:22][C:23](=[O:25])[CH3:24])=[N:19][C:18]=2[CH3:26])=[CH:8][CH:7]=1)([O:3]CC)=[O:2].[OH-].[Na+]>>[C:1]([C:6]1[CH:11]=[CH:10][C:9]([CH2:12][CH2:13][NH:14][CH2:15][CH:16]([OH:27])[C:17]2[S:21][C:20]([NH:22][C:23](=[O:25])[CH3:24])=[N:19][C:18]=2[CH3:26])=[CH:8][CH:7]=1)([OH:3])=[O:2]

Komponenten

3

Edukt 2

HCID 14798Sodium HydroxideHCID 14076218HCID 14076218, Verbindung

Produkt 1

HCID 14076219HCID 14076219, Verbindung

Versuchsvorschrift

Prepared analogously to Example 2 by reaction of N-[2-(4-carboethoxyphenyl)ethyl]-2-hydroxy-2-(2-acetylamino-4-methyl-thiazol-5-yl)ethanamine with 1N sodium hydroxide solution. After neutralisation with 1N hydrochloric acid, the mixture is evaporated to dryness, and the residue is recrystallised from 10 ml of water.

Aufarbeitung

  1. customAfter neutralisation with 1N hydrochloric acid, the mixture is evaporated to dryness
  2. customthe residue is recrystallised from 10 ml of water

Quellen und Nachweise

ORD-Eintrag
ord-0ab5ff77497946208d059ab5d2d549aa
Quelldatensatz
uspto-grants-1993_06
Patentnummer
US05219852

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