Glycine → HCID 13917964, Verbindung

HRID 1590968Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1590968
[NH2:1][CH2:2][C:3]([OH:5])=[O:4].[NH:6]([C:28]([O:30][C:31]([CH3:34])([CH3:33])[CH3:32])=[O:29])[C@H:7]([C:18](ON1C(=O)CCC1=O)=[O:19])[C@@H:8]([CH3:17])[O:9][CH2:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1>>[NH:6]([C:28]([O:30][C:31]([CH3:32])([CH3:34])[CH3:33])=[O:29])[C@H:7]([C:18]([NH:1][CH2:2][C:3]([OH:5])=[O:4])=[O:19])[C@@H:8]([CH3:17])[O:9][CH2:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1

Komponenten

3

Edukt 2

HCID 750GlycineHCID 12879029Boc-Thr(Bzl)-OSu

Produkt 1

HCID 13917964HCID 13917964, VerbindungAusbeute 97,3 %

Versuchsvorschrift

By using 5.40 g of H-Gly-OH and 22.40 g of Boc-Thr(Bzl)-OSu, and the same procedure as in Reference Example 14 was repeated to obtain 19.60 g (yield: 97.3%) of the above-mentioned objective product.

Quellen und Nachweise

ORD-Eintrag
ord-4aee15e6777c4b0b9d95210fecd395ca
Quelldatensatz
uspto-grants-1993_04
Patentnummer
US05204326

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