N-(4-Aminobutyl)-N-methyl carbamic acid tert-butyl ester → {4-[(3,5-Dimethyl-pyridin-2-ylmethyl)-amino]-butyl}-methyl-carbamic acid tert-butyl ester

HRID 1592375

Reaktionsgleichung

Reaktionsgleichung von HRID 1592375
[CH3:1][C:2]1[C:3]([CH:9]=O)=[N:4][CH:5]=[C:6]([CH3:8])[CH:7]=1.[C:11]([O:15][C:16](=[O:24])[N:17]([CH2:19][CH2:20][CH2:21][CH2:22][NH2:23])[CH3:18])([CH3:14])([CH3:13])[CH3:12]>>[C:11]([O:15][C:16](=[O:24])[N:17]([CH2:19][CH2:20][CH2:21][CH2:22][NH:23][CH2:9][C:3]1[C:2]([CH3:1])=[CH:7][C:6]([CH3:8])=[CH:5][N:4]=1)[CH3:18])([CH3:14])([CH3:12])[CH3:13]

Komponenten

3

Edukt 2

HCID 2756377N-(4-Aminobutyl)-N-methyl carbamic acid tert-butyl esterHCID 187316833,5-Dimethylpyridine-2-carbaldehyde

Produkt 1

HCID 58997083{4-[(3,5-Dimethyl-pyridin-2-ylmethyl)-amino]-butyl}-methyl-carbamic acid tert-butyl ester

Versuchsvorschrift

Yellow oil prepared from 3,5-dimethyl-pyridine-2-carbaldehyde and (4-amino-butyl)-methyl-carbamic acid tert-butyl ester. 1H NMR (CDCl3) δ 1.44 (s, 9H), 1.53-1.57 (m, 4H), 2.27 (s, 6H), 2.69-2.73 (m, 2H), 2.82 (s, 3H), 3.18-3.23 (m, 2H), 3.83 (s, 2H), 7.24 (s, 1H), 8.20 (s, 1H).

Quellen und Nachweise

ORD-Eintrag
ord-6ae80f4c59544f75936b281d881a6fa9
Quelldatensatz
uspto-grants-2007_11
Patentnummer
US07291631B2

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