3-(Dimethylamino)-1-(4-fluorophenyl)-2-(pyridin-4-yl)prop-2-en-1-one → HCID 178505663, Verbindung
Reaktionsgleichung
C[N:2](C)[CH:3]=[C:4]([C:14]1[CH:19]=[CH:18][N:17]=[CH:16][CH:15]=1)[C:5]([C:7]1[CH:12]=[CH:11][CH:10]=[C:9]([F:13])[CH:8]=1)=O.C[N:22](C)C=C(C1C=CN=CC=1)C(C1C=CC(F)=CC=1)=O>>[F:13][C:9]1[CH:8]=[C:7]([C:5]2[C:4]([C:14]3[CH:19]=[CH:18][N:17]=[CH:16][CH:15]=3)=[CH:3][NH:2][N:22]=2)[CH:12]=[CH:11][CH:10]=1Komponenten
3
Versuchsvorschrift
The reaction was carried out in the same manner as in Example 1-2) except for using 18.3 g (67.7 mmol) of 3-dimethylamino-1-(3-fluorophenyl)-2-(pyridin-4-yl)-2-propen-1-one obtained in Example 7-1) in place of 3-dimethylamino-1-(4-fluorophenyl)-2-(pyridin-4-yl)-2-propen-1-one to obtain 11.3 g of the title compound as a white powder. (Yield: 70%)
Quellen und Nachweise
- ORD-Eintrag
- ord-eae09fec9eab4024ad8d439c241bd009