Methyl iodide → N,N-Diethyl-2-methoxy-N-methylethan-1-aminium iodide

HRID 1593346Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1593346
[CH3:1][O:2][CH2:3][CH2:4][N:5]([CH2:8][CH3:9])[CH2:6][CH3:7].[CH3:10][I:11]>O1CCCC1>[I-:11].[CH3:1][O:2][CH2:3][CH2:4][N+:5]([CH2:8][CH3:9])([CH2:6][CH3:7])[CH3:10]

Komponenten

4

Edukt 2

HCID 6328Methyl iodideHCID 113555002-methoxyethyldiethylamine

Produkt 1

HCID 71374868N,N-Diethyl-2-methoxy-N-methylethan-1-aminium iodide

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 8028TetrahydrofuranLösungsmittel

Versuchsvorschrift

Next, 8.24 g of the 2-methoxyethyldiethylamine was dissolved in 10 ml of tetrahydrofuran (Wako Pure Chemical Industries), following which 4.0 ml of methyl iodide (Wako Pure Chemical Industries) was added under ice cooling. After 30 minutes, the mixture was removed from the ice bath and stirred overnight at room temperature. The solvent in the resulting reaction mixture was then driven off by vacuum distillation, and the resulting solids were recrystallized from an ethanol (Wako Pure Chemical Industries)-tetrahydrofuran system, yielding 16 g of 2-methoxyethyldiethylmethylammonium iodide.

Aufarbeitung

  1. additionwas added under ice cooling
  2. customthe mixture was removed from the ice bath
  3. customThe solvent in the resulting reaction mixture
  4. distillationwas then driven off by vacuum distillation
  5. customthe resulting solids were recrystallized from an ethanol (Wako Pure Chemical Industries)-tetrahydrofuran system

Quellen und Nachweise

ORD-Eintrag
ord-c874a9245ca94705b04cdafbe3025f31
Quelldatensatz
uspto-grants-2007_11
Patentnummer
US07297289B2

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