Dimethylformamide → 4-(2-(Dimethylamino)ethyl)benzaldehyde
Reaktionsgleichung
Br[C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH2:9][N:10]([CH3:12])[CH3:11])=[CH:4][CH:3]=1.[Mg].CN([CH:17]=[O:18])C>>[CH3:11][N:10]([CH3:12])[CH2:9][CH2:8][C:5]1[CH:6]=[CH:7][C:2]([CH:17]=[O:18])=[CH:3][CH:4]=1Komponenten
4
Versuchsvorschrift
2-(4-Bromophenyl)-N,N-dimethylethylamine (6.8 g) was refluxed under heating with magnesium for 1 hr to prepare a Grignard reagent, which was reacted with DMF to give the objective 4-(2-dimethylaminoethyl)benzaldehyde as an oil (4.2 g).
Quellen und Nachweise
- ORD-Eintrag
- ord-3829d2f2230f418abd08f4b1fb067420
- Quelldatensatz
- uspto-grants-2001_09
- Patentnummer
- US06288061B1
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