HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Phenylpropanolamine → (1S,2R)-2-amino-1-phenylpropan-1-ol
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Phenylpropanolamine | HCID 10297 | — |
| Edukt | Sodium borohydride | HCID 4311764 | — |
| Lösungsmittel | Ethanol | HCID 702 | — |
| Produkt | (1S,2R)-2-amino-1-phenylpropan-1-ol | HCID 26934 | — |
Reaktionsschritte
As shown in the scheme above, (1R, 2S)-(−)- norephedrine is reacted with an optionally substituted benzaldehyde by refluxing in ethanol, and reducing the product of that reaction with sodium borohydride at ambient temperature to produce the desired norephedrine derivative compound.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06288233B1 |
| Quelldatensatz | uspto-grants-2001_09 |
| ORD ID | ord-b28c151d057f4f0bbcfc10c69ab8201e |
| Quellennotiz | uspto-grants-2001_09 |