1-Bromonaphthalene-2-carbaldehyde → (1-Bromonaphthalen-2-yl)methanol

Beteiligte Stoffe

Reaktionsschritte

A solution of 1-bromo-2-naphthaldehyde (2.12 g, 8.91 mmol) in MeOH under N2 at 0° C. was treated with NaBH4 (0.51 g, 13.4 mmol), stirred for 15 minutes, quenched with acetone, and concentrated. Purification on silica gel with 5% ethyl acetate/CH2Cl2 provided 1.95 g (92%) of the desired compound as a white solid.

Herkunft & Nachweise