2-Methoxyphenylacetic acid → HCID 67660569, Verbindung
Reaktionsgleichung
Cl.[C:2]([CH2:4][CH:5]1[CH2:13][CH:12]2[CH:8]([CH2:9][NH:10][CH2:11]2)[C:7]([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)([OH:14])[CH2:6]1)#[N:3].[CH3:21][O:22][C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][C:24]=1[CH2:29][C:30](O)=[O:31]>>[C:2]([CH2:4][CH:5]1[CH2:13][CH:12]2[CH:8]([CH2:9][N:10]([C:30](=[O:31])[CH2:29][C:24]3[CH:25]=[CH:26][CH:27]=[CH:28][C:23]=3[O:22][CH3:21])[CH2:11]2)[C:7]([C:15]2[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=2)([OH:14])[CH2:6]1)#[N:3]Komponenten
3
Versuchsvorschrift
The procedure is as described in Example 14 beloW, starting from 0.63 g of (3aRS,4RS,6RS,7aSR)-6-cyanomethyl-4-phenylperhydroisoindol-4-ol hydrochloride and 0.39 g of 2-methoxyphenylacetic acid, and gives 0.56 g of (3aRS,4RS,6RS,7aSR)-6-cyanomethyl-4-phenyl-2-(2-methoxyphenylacetyl)perhydroisoindol-4-ol in the form of a thick white foam.
Quellen und Nachweise
- ORD-Eintrag
- ord-cef052e7d4954a5cb4bcf58b04a6c53f
- Quelldatensatz
- uspto-grants-1998_04