Fumarate → 5-Methyl-2-(1-methyl-1,2,5,6-tetrahydro-3-pyridyl)-thiazole

HRID 1600453Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1600453
[CH3:1][C:2]1[S:6][C:5]([C:7]2[CH:8]=[N:9][CH:10]=[CH:11][CH:12]=2)=[N:4][CH:3]=1.[C:13]([O-])(=O)/C=C/C([O-])=O>>[CH3:1][C:2]1[S:6][C:5]([C:7]2[CH2:8][N:9]([CH3:13])[CH2:10][CH2:11][CH:12]=2)=[N:4][CH:3]=1

Komponenten

3

Edukt 2

HCID 5460307FumarateHCID 196125135-Methyl-2-(3-pyridyl)-thiazole

Produkt 1

HCID 196124795-Methyl-2-(1-methyl-1,2,5,6-tetrahydro-3-pyridyl)-thiazole

Versuchsvorschrift

The title compound was prepared from 88 (2.2 g, 0.013 mol) by the procedure described in Example 49. The crude free base obtained, 89, was converted to the title fumarate, 90. Yield: 0.8 g (0.0032 mol, 25%). M.P. 159°-160° C. Anal. (C12H16N2O2S)C, H, N.

Aufarbeitung

  1. customThe crude free base obtained

Quellen und Nachweise

ORD-Eintrag
ord-1f3d63b3d76045508493ba53e1f22655
Quelldatensatz
uspto-grants-1999_11
Patentnummer
USRE036374

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