2-Naphthalenethiol → HCID 21830630, Verbindung

HRID 1600893Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1600893
[CH:1]1[CH:10]=[C:9]2[C:4]([CH:5]=[C:6]([SH:11])[CH:7]=[CH:8]2)=[CH:3][CH:2]=1.[N:12]1[CH:17]=[CH:16][CH:15]=[C:14]([CH2:18][CH2:19][C:20](=[O:23])[CH:21]=[CH2:22])[CH:13]=1>C(O)C>[N:12]1[CH:17]=[CH:16][CH:15]=[C:14]([CH2:18][CH2:19][C:20](=[O:23])[CH2:21][CH2:22][S:11][C:6]2[CH:7]=[CH:8][C:9]3[C:4](=[CH:3][CH:2]=[CH:1][CH:10]=3)[CH:5]=2)[CH:13]=1

Komponenten

4

Edukt 2

HCID 70582-NaphthalenethiolHCID 218306261-(3-Pyridyl)-4-penten-3-one

Produkt 1

HCID 21830630HCID 21830630, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Versuchsvorschrift

2-Thionaphthol was added to a solution of 1-(3-pyridyl)-4-penten-3-one (0.200 g) in ethanol (30 ml) followed by stirring overnight at room temperature. The ethanol was removed under reduced pressure and the residue purified by column chromatography over silica eluting with dichloromethane:ethyl acetate (2:1) to give the sub-title compound as a white solid (0.142 g).

Aufarbeitung

  1. customThe ethanol was removed under reduced pressure
  2. customthe residue purified by column chromatography over silica eluting with dichloromethane:ethyl acetate (2:1)

Quellen und Nachweise

ORD-Eintrag
ord-59a8a781c3df46478763d2b69215da3e
Quelldatensatz
uspto-grants-1999_11
Patentnummer
US05977105

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