Sulfuric Acid → Methyl 3-(4-hydroxyphenyl)benzoate

HRID 1600944Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1600944
[C:1]([C:4]1[CH:5]=[C:6]([C:10]2[CH:15]=[CH:14][C:13]([OH:16])=[CH:12][CH:11]=2)[CH:7]=[CH:8][CH:9]=1)([OH:3])=[O:2].S(=O)(=O)(O)O.[C:22](=O)([O-])O.[Na+]>CO>[CH3:22][O:2][C:1]([C:4]1[CH:5]=[C:6]([C:10]2[CH:15]=[CH:14][C:13]([OH:16])=[CH:12][CH:11]=2)[CH:7]=[CH:8][CH:9]=1)=[O:3]

Komponenten

5

Edukt 3

HCID 1118Sulfuric AcidHCID 516892Sodium BicarbonateHCID 7224324'-Hydroxy-biphenyl-3-carboxylic acid

Produkt 1

HCID 5097337Methyl 3-(4-hydroxyphenyl)benzoate

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 887MethanolLösungsmittel

Versuchsvorschrift

Solid 3'-carboxybiphenyl-4-ol (1.5 g) was suspended in methanol (10 ml) and concentrated sulfuric acid (1 ml). The mixture was heated at reflux for 16 hours. After cooling, the mixture was basified by the addition of solid sodium hydrogen carbonate. The white solid which formed was filtered and washed with copious amounts of water to give the sub-title compound as a white solid (1.5 g).

Aufarbeitung

  1. temperatureThe mixture was heated
  2. temperatureat reflux for 16 hours
  3. temperatureAfter cooling
  4. customThe white solid which formed
  5. filtrationwas filtered
  6. washwashed with copious amounts of water

Quellen und Nachweise

ORD-Eintrag
ord-dbef5c807bcf487797086022dff1f618
Quelldatensatz
uspto-grants-1999_11
Patentnummer
US05977105

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