Methyl iodide → Quinoline

HRID 1601011Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1601011
C(=O)([O-])[O-].[K+].[K+].[Na].[H][H].CI.C(I)CC.[CH2:16](I)[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1.[CH2:24]([N:26](CC)CC)[CH3:25]>>[N:26]1[C:22]2[C:17](=[CH:18][CH:19]=[CH:20][CH:21]=2)[CH:16]=[CH:25][CH:24]=1

Komponenten

7

Edukt 6

HCID 6328Methyl iodideHCID 8471TriethylamineHCID 11430Potassium CarbonateHCID 12098Benzyl iodideHCID 336431-IodopropaneHCID 178506446HCID 178506446, Verbindung

Produkt 1

HCID 7047Quinoline

Versuchsvorschrift

To the solution is added one equivalen to a small excess amount of a base, e.g. potassium carbonate, triethylamine, sodium hydrogen, one equivalent to excess amount of halogens alkyl derivative, e.g. methyl iodide, propyl iodide, benzyl iodide, and the mixture is stirred at a temperature of 0° C. to 80° C. to give a quinoline derivative (ivz).

Quellen und Nachweise

ORD-Eintrag
ord-c4facb2c96494b0bac7adcbe17d752ca
Quelldatensatz
uspto-grants-1999_11
Patentnummer
US05977132

Notizen zur Reaktion

Wird geladen…