Tetrahydrofuran → 1-Diallylcarbamoyl-3-isopropylsulphinyl-1,2,4-triazole

HRID 1606065Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1606065
[CH:1]([S:4]([C:6]1[N:10]=[CH:9][NH:8][N:7]=1)=[O:5])([CH3:3])[CH3:2].[CH2:11]([N:14]([CH2:18][CH:19]=[CH2:20])[C:15](Cl)=[O:16])[CH:12]=[CH2:13].O1CCCC1>C(N(CC)CC)C>[CH2:11]([N:14]([CH2:18][CH:19]=[CH2:20])[C:15]([N:8]1[CH:9]=[N:10][C:6]([S:4]([CH:1]([CH3:3])[CH3:2])=[O:5])=[N:7]1)=[O:16])[CH:12]=[CH2:13]

Komponenten

5

Edukt 3

HCID 8028TetrahydrofuranHCID 3449313Diallylcarbamyl chlorideHCID 1784610013-Isopropylsulphinyl-1,2,4-triazole

Produkt 1

HCID 203550491-Diallylcarbamoyl-3-isopropylsulphinyl-1,2,4-triazole

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 8471TriethylamineLösungsmittel

Versuchsvorschrift

A mixture of 6.4 g. 3-isopropylsulphinyl-1,2,4-triazole, 8.0 ml. diallylcarbamoyl chloride, 25 ml. dry tetrahydrofuran and 10 ml. dry triethylamine was refluxed under anhydrous conditions for 2 hours. The cooled reaction mixture was filtered and the filtrate was distilled under reduced pressure to give an oily residue which subsequently solidified. This solid residue was recrystallized from petroleum ether (b.p. 60° - 80°C.) to give 1-diallylcarbamoyl-3-isopropylsulphinyl-1,2,4-triazole, m.p. 32° - 34°C. Elemental analysis satisfactory. EXAMPLE 19

Aufarbeitung

  1. additionA mixture of 6.4 g
  2. customThe cooled reaction mixture
  3. filtrationwas filtered
  4. distillationthe filtrate was distilled under reduced pressure
  5. customto give an oily residue which
  6. customThis solid residue was recrystallized from petroleum ether (b.p. 60° - 80°C.)

Quellen und Nachweise

ORD-Eintrag
ord-6720ec3f750a4b28b9eaac6d58f28bbd
Quelldatensatz
uspto-grants-1976_04
Patentnummer
US03952001

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