Methylamine → 1-Nitro-2-methylamino-2-[2-((4-bromo-5-imidazolyl)methylthio)ethylamino]ethylene

HRID 1606548

Reaktionsgleichung

Reaktionsgleichung von HRID 1606548
[Br:1][C:2]1[N:3]=[CH:4][NH:5][C:6]=1[CH2:7][S:8][CH2:9][CH2:10][NH2:11].[N+:12]([CH:15]=[C:16](SC)SC)([O-:14])=[O:13].[CH3:21][NH2:22]>>[N+:12]([CH:15]=[C:16]([NH:22][CH3:21])[NH:11][CH2:10][CH2:9][S:8][CH2:7][C:6]1[NH:5][CH:4]=[N:3][C:2]=1[Br:1])([O-:14])=[O:13]

Komponenten

4

Edukt 3

HCID 6329MethylamineHCID 836231,1-Bis(methylthio)-2-nitroethyleneHCID 127889492-(((5-Bromo-1H-imidazol-4-yl)methyl)thio)ethanamine

Produkt 1

HCID 705440051-Nitro-2-methylamino-2-[2-((4-bromo-5-imidazolyl)methylthio)ethylamino]ethylene

Versuchsvorschrift

When 4-bromo-5-[(2-aminoethyl)thiomethyl]imidazole (from the dihydrobromide (4.8 g)) is reacted with 1-nitro-2,2-bis-methylthioethylene (2.0 g) according to the procedure of Example 4(i) and the resultant 1-nitro-2-methylthio-2- 2-((4-bromo-5-imidazolyl)methylthio)ethylamino ethylene treated with methlyamine by the procedure of Example 3(ii) there is produced 1-nitro-2-methylamino-2-[2-((4-bromo-5-imidazolyl)methylthio)ethylamino] ethylene.

Quellen und Nachweise

ORD-Eintrag
ord-41737802ca454b37a0828a46bc87eb72
Quelldatensatz
uspto-grants-1976_04
Patentnummer
US03953460

Verknüpfte Notizen

Wird geladen…