2-Quinolinecarboxaldehyde → HCID 54189210, Verbindung

HRID 1608176

Reaktionsgleichung

Reaktionsgleichung von HRID 1608176
[N:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][C:2]=1[CH:11]=O.[C:13]1([CH3:23])[CH:18]=[CH:17][CH:16]=[C:15]([C:19]([NH:21][NH2:22])=[O:20])[CH:14]=1>C(O)C>[N:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][C:2]=1[CH:11]=[N:22][NH:21][C:19](=[O:20])[C:15]1[CH:16]=[CH:17][CH:18]=[C:13]([CH3:23])[CH:14]=1

Komponenten

4

Edukt 2

HCID 796192-QuinolinecarboxaldehydeHCID 83082m-Toluohydrazide

Produkt 1

HCID 54189210HCID 54189210, VerbindungAusbeute 36,2 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Versuchsvorschrift

A mixture of 3.3 gm (0.021 mole) of 2-quinolinecarboxaldehyde, 3.15 gm (0.021 mole) of m-toluic acid hydrazide and 150 ml of absolute ethanol is refluzed 10 hr. The hot solution is filtered then diluted with water until cloudy. The mixture is cooled to room temperature and then chilled. The solid is collected to give 2.2 gm (36%) of the title compound having a melting point of 187.5°-188° C. after recrystallizing from methylene chloride/diethyl ether.

Aufarbeitung

  1. filtrationThe hot solution is filtered
  2. additionthen diluted with water until cloudy
  3. temperaturechilled
  4. customThe solid is collected

Quellen und Nachweise

ORD-Eintrag
ord-7d855082c6a547da820846c7f6518b6e
Quelldatensatz
uspto-grants-1989_09
Patentnummer
US04870082

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