2-Methylpyrrolidine → 1-[(3,5'-Dichloro-2'-methoxy[1,1'-biphenyl]-4-yl)carbonyl]-2-methyl-pyrrolidine
Reaktionsgleichung
[Cl:1][C:2]1[CH:3]=[C:4]([C:18]2[CH:23]=[C:22]([Cl:24])[CH:21]=[CH:20][C:19]=2[O:25][CH2:26]C(O)=O)[CH:5]=[CH:6][C:7]=1[C:8]([N:10]1[C@@H:15](C)[CH2:14][CH2:13]C[C@H:11]1[CH3:17])=[O:9].CC1CCCN1>>[Cl:1][C:2]1[CH:3]=[C:4]([C:18]2[CH:23]=[C:22]([Cl:24])[CH:21]=[CH:20][C:19]=2[O:25][CH3:26])[CH:5]=[CH:6][C:7]=1[C:8]([N:10]1[CH2:15][CH2:14][CH2:13][CH:11]1[CH3:17])=[O:9]Komponenten
3
Versuchsvorschrift
The sub-title compound was prepared by the method of example 18 step a) using the product of step example 21 step a) and 2-methylpyrrolidine.
Quellen und Nachweise
- ORD-Eintrag
- ord-f89d528f07aa40eab0876808d4b23adb
- Quelldatensatz
- uspto-grants-2010_06