Trifluoroacetic acid → HCID 67805215, Verbindung

HRID 1609619Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1609619
[CH2:1]([O:8][C:9]([CH:11]1[CH2:19][CH:18]2[CH:13]([CH2:14][CH2:15][CH2:16][CH2:17]2)[N:12]1[C:20](=[O:31])[C@H:21]([CH3:30])[NH:22]C(OC(C)(C)C)=O)=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[F:32][C:33]([F:38])([F:37])[C:34]([OH:36])=[O:35]>>[F:32][C:33]([F:38])([F:37])[C:34]([OH:36])=[O:35].[CH2:1]([O:8][C:9]([CH:11]1[CH2:19][CH:18]2[CH:13]([CH2:14][CH2:15][CH2:16][CH2:17]2)[N:12]1[C:20](=[O:31])[C@H:21]([CH3:30])[NH2:22])=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Komponenten

3

Edukt 2

HCID 6422Trifluoroacetic acidHCID 67806908HCID 67806908, Verbindung

Produkt 1

HCID 67805215HCID 67805215, Verbindung

Versuchsvorschrift

21.5 g of Boc-Ala-Oic-OBzl are dissolved in 50 ml of trifluoroacetic acid. The solution is concentrated in vacuo, and the residue is digested several times with diisopropyl ether and is dried in vacuo. Yield: 21 g. The proton signal for the tertiary-butyl group is completely absent in the NMR spectrum.

Aufarbeitung

  1. concentrationThe solution is concentrated in vacuo
  2. customis dried in vacuo

Quellen und Nachweise

ORD-Eintrag
ord-8a009f164b1d445291641c52e51200e5
Quelldatensatz
uspto-grants-1995_03
Patentnummer
US05401766

Notizen zur Reaktion

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